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Traditional treatments like dopamine replacement and DBS primarily manage symptoms without altering the disease course

We circumvented the need for CYP-mediated bioactivation of AQ and DEAQ by exposing the cells to the synthetic AQ-QI and DEAQ-QI, the reactive metabolites of AQ

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marneffei Gst protein family Gsts comprise a complex and widespread enzyme family, and therefore we utilized the KEGG pathway map and BLAST program to search for Gst encoding genes