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Some studies lack placebo controls or do not differentiate between responders and non-responders

doi: 10.1017/s0007114517002112 125 ManiraroraJNKosiewicz MMPA

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Although bitter kola is mostly used among pregnant women to treat nausea and vomiting (Laelago, 2018), reported pharmacological effects of this plant include anti-diabetic, anti-inflammatory, antipyretic, immunomodulatory, anti-atherogenic, anti-microbial, and hepaprotective effects (Okoye et al., 2014)