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Reduced cytotoxic function of effector CD8+ T cells is responsible for indoleamine 2,3-dioxygenase-dependent immune suppression

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Conserved region 3 (CR3) of human FOXO4 was similarly modelled by I-TASSER using the NMR structure of the CR3 domain of FOXO3 (PDB ID: 2LQH) [20] as the template

[DOI] [PubMed] [Google Scholar] 51