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LW, CZ, and JZ searched and summarized the literature, LW wrote the manuscript

10.1182/blood.V92.9.3007

10.1126/sciadv.aaw4543 281 TonjesM.BarbusS.ParkY

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Its key enzymes and the entire pathway not only act as driving factors of tumor development, but also provide theoretical support and potential targets for targeted therapy and its combination with immunotherapy
