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5,10-Methylene tetrahydrofolate (THF) is required for the synthesis of nucleic acids and is reduced to 5-methyl THF by methylene THF reductase, a flavin-dependent enzyme that uses NADPH as a cofactor

Essentially, the contribution of HIV-TAT to binding free energy ( Fig

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X-inactivation Females carry two copies of the X chromosome and therefore could potentially express toxic levels (a 'double dose') of X chromosome-linked genes