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If neurological symptoms worsen or fail to improve after four to six weeks of appropriate treatment , further investigation is necessary to exclude alternative diagnoses or complications
In addition, RAS-selective lethal three induced-RPE ferroptosis shows the features of receptor-interacting protein kinase (RIPK)1/RIPK3 activation and lipid ROS accumulation (Tong et al., 2023)
doi: 10.7759/cureus.4985
Some users notice subtle metabolic changes like increased energy or reduced appetite within the first 1-2 weeks
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