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Finally, interaction with other proteins and post-translational modifications can affect the expression and activity of SLC7A11

When combined with cisplatin, delphinidin significantly enhances the chemotherapeutic effect of cisplatin by inhibiting MDR1 expression (Sun et al., 2023)

Toll-like receptor 4 mediates methamphetamine-induced neuroinflammation through caspase-11 signaling pathway in astrocytes

Without treatment, WD is fatal and is best managed by a multidisciplinary team including neurologists, hepatologists, pharmacists and dietitians[6]
