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Banks and Kastin reported that radiolabeled DSIP administered peripherally produced detectable DSIP-like immunoreactivity in brain tissue at levels above what non-specific leakage would predict, and that the modified analogue [D-Ala3]-DSIP entered brain at substantially higher levels than the parent compound after intracarotid administration (Banks & Kastin, 1981)
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The lower mintage compared to P-mint coins makes well-preserved D examples slightly more desirable to collectors

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