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The blocking of miR-27a-3p and miR-27b-3p through miRNA inhibitors prevents the anti-adipogenic effect of VitD in both cell models

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AOD9604 was originally developed after research on mice, but subsequent studies in human have shown no efficacy for the potential treatment of obesity.

The same symptoms can come from very different biology: EPI is often managed with lifelong enzyme replacement, while PLE involves intestinal protein loss, swelling, and higher short-term mortality

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