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In those studies with a positive association between D2 polymorphisms and metabolic disease, it is strongest when combining the D2 gene polymorphism with a polymorphism in a gene from another interacting metabolic pathway, such as the 3 adrenergic receptor (174), or PPAR (70)

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Interestingly, in a group of seven vegans/vegetarians given 500 mg/day of supplemental L-carnitine for two to three months, only three demonstrated increased GBB-to-TMA conversion.6 There could be a genetic explanation

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