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This duality underscores the importance of context-specific modulation and highlights the current lack of reliable biomarkers to guide patient selection for autophagy-targeting combinations

Interestingly, also mRNA levels of mmp9, p62, atg5 and lc3b did not differ between brains of treated and control gr / zebrafish (Fig

While the dysbiosis-mediated induction of LGS initiates an inflammatory response, some microbial products reinforce TJ integrity

IL33-STAT3-MMP2/9 is reported to play an important role in macrophage polarization from anti-inflammatory phenotype (M2) to proinflammatory phenotype (M1), thus inducing lipopolysaccharide (LPS)-induced ALI and pulmonary inflammation

Methylated metabolites of arsenic trioxide are more potent than arsenic trioxide as apoptotic but not differentiation inducers in leukemia and lymphoma cells