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In dogs affected with atypical hyperadrenocorticism caused by sex steroid overproduction, dermatologic changes (alopecia, poor hair coat) and reproductive manifestations (perianal adenoma in a castrated male or female dog) are often the only signs suggestive of sex steroid imbalance

Use this guide to help tailor your serum choice to ensure optimal results and address your primary concerns effectively: Face Serum for Dry Skin: For dry skin, the focus should be on intense hydration

Danijela Kolenc, Email: [email protected]

*Correspondence: Hakan Kulacoglu, [email protected] Specialty section: This article was submitted to Visceral Surgery, a section of the journal Frontiers in Surgery Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Rational combination strategies that simultaneously target multiple metabolic pathways, or integrate metabolic inhibitors with chemotherapy, targeted therapy, or immunotherapy, warrant further investigation