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doi:10.14670/HH-23.381

Interestingly, in 4 of 5 subjects, the early antibody response was primarily directed towards the Fc domain, but over time, shifted to primarily recognize the Fab domains ( Figure 4B )

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The impact of genetic removal of GFAP and/or vimentin on glutamine levels and transport of glucose and ascorbate in astrocytes

Although those suffering from CGD exhibit a wide range of clinical symptoms, ranging from a relatively mild presentation late in life to fatal septicemia in infancy, X-linked CYBB CGD generally causes more severe infections and earlier deaths than autosomal recessive CGD (Holland, 2013