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Melanin-like nanoparticles as an alternative to natural melanin in retinal pigment epithelium cells and their therapeutic effects against age-related macular degeneration

However, the hormesis model describes a biphasic response in which low to moderate exposure to ROS/RNS stimulates the adaptive upregulation of endogenous antioxidants, thereby improving cellular function

Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release

hPSCs-derived brain organoids for disease modeling, toxicity testing and drug evaluation

CAT is an enzyme that converts hydrogen peroxide into water and oxygen, playing a crucial role in reducing hydrogen peroxide generated by SOD and other metabolic processes in peroxisomes, and that exhibits different effects based on hydrogen peroxide concentrations [Sepasi Tehrani & MoosaviMovahedi, 2018]