glutathione peptide cycle - an overview Glutathione in Brain Disorders and

However, the dual role of lactate is evident as it also contributes to the progression of myocardial fibrosis and worsens cardiac dysfunction by facilitating endothelial-mesenchymal transition (EndoMT) following MI [133]

J., Salo, K

The antifungal agent ketoconazole has a dual role in hair loss compounding: it reduces Malassezia overgrowth on the scalp (a contributor to follicular inflammation and seborrheic dermatitis) and has demonstrated weak anti-androgenic properties

Microbiome-derived inosine modulates response to checkpoint inhibitor immunotherapy

However, since NO is freely diffusible across membranes, it is possible that the mitochondrial production of peroxynitrite may derive from extramitochondrial NO diffusing into mitochondria to react with superoxide generated by ETC