glutathione increase after treating with platinum drugs A cisplatin-based platinum(IV) prodrug containing a s-transferase inhibitor to reverse cisplatin-resistance in non-small cell lung cancer The crosstalk between glutathione metabolism

For instance, CCS and copper are essential for hypoxia-induced formation of the hypoxia-inducible factor 1 (HIF-1)/E1A binding protein p300 complex in hepatocellular carcinoma [87], which likely inhibits cuproptosis [88], while ATOX1 acts as a copper-dependent transcription factor in endothelial and cancer cells [89]

[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Noctor G., Queval G., Mhamdi A., Chaouch S., Foyer C.H

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