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Conflicts of interest The other authors have declared that no conflict of interest exists

Other curves show the responses to giving different amounts of NAC over this one hour period

Of these four genes, mutations in the Cu/Zn superoxide dismutase SOD1 , a copper-dependent enzyme that is important in detoxification of superoxide radicals, has been studied the longest as it was first identified as an ALS-associated mutation in the early 1990s (Rosen et al., 1993

In these areas, it helps stabilize cell structures and shields DNA from damage caused by free radicals, which contribute to aging and disease

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