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Structural and functional abnormalities in the amygdala, hippocampus and medial prefrontal cortex underlie persistent, overgeneralized fear responses (Xue et al., 2015) with prevalence rates twice as high in females than in males (Perrin et al., 2014)

Increased sensitivity to salinity/drought and higher stress-induced ROS production was also found in low AsA mutants (Huang et al., 2005

Clinical Cancer Research 29(4):711-722, 2023

As GCase does not cross the bloodbrain barrier, the development of small-molecule chaperones to correct GCase folding and thus enhance GCase activity and lysosomal function is a feasible strategy [149]

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