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Q5: Why are scientists interested in NNMT inhibition

longum ), has been demonstrated to hasten the SARS-CoV-2 antibody formation, reduce the nasopharyngeal viral load and pro-inflammatory markers, and restore gut dysbiosis in patients with COVID-19 (Zhang L

Intracellular concentrations decline with age and oxidative stress exposure

The result is that conjugated bile acids are almost totally ionized at the pH prevailing in the small intestinal lumen and thus cannot passively traverse cell membranes

Gustin et al
