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Macrophages (polarized and non-polarized, stimulated and unstimulated) were pretreated with 40100 M KL1, 20 M BHA or 0.10.25% DMSO in 500 l complete medium at 37 C for 1 h in triplicates
Involvement of the GPx-1 gene locus in LOH events has been shown for cancers of the lung, breast, head and neck, and colon (159, 174176, 260)
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4,6-Diamidino-2-phenylinodole (DAPI

Abbreviations 2OBA: 2-Oxobutanoate 3PG: 3-Phosphoglycerate AUC: Area under the receiver operating characteristic (ROC) curve BILAG: British Isles Lupus Assessment Group cAMP: Cyclic AMP db-cAMP: Dibutyryl cAMP DHAP: Dihydroxy-acetone-phosphate DN T: CD3 + CD4 CD8 double-negative T cell E4P: Erythrose 4-phosphate FAS: Fatigue assessment scale FDR: False discovery rate G1P: Glucose 1-phosphate G6P: Glucose 6-phosphate GA3P: Glyceraldehyde 3-phosphate GL6P: Gluconolactone 6-phosphate GPP: Geranyl pyrophosphate GSH: Reduced glutathione GSSG: Oxidized glutathione HCA: Homocysteic acid HCY: Homocysteine HE: Hydroethidine;ROI sensor IAA: Indol-3-acetic acid Kyn: Kynurenine LCMS/MS: Liquid chromatography-tandem mass spectroscopy Met-SO: Methionine sulfoxide mTOR: Mammalian/mechanistic target of rapamycin NAC: N -acetylcysteine O8P: Octulose 8-phosphate OAA: Oxaloacetate PBL: Peripheral blood lymphocytes PBS: Phosphate buffered saline PCA: Principal component analysis PLS-DA: Partial least square-discriminant analysis PI: Propidium iodide R5P: Ribose 5-phosphate RFI: Relative fluorescence intensity ROC: Receiver operating characteristic S7P: Sedoheptulose 7-phosphate SBP: Sedoheptulose 1,7-bisphosphate SLE: Systemic lupus erythematosus SLEDAI: Systemic lupus erythematosus disease activity index SPE: Squared prediction errors T6P: Trehalose 6-phosphate VIP: Variable importance in projection References Aune, T
