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When the gut lining is compromised, patients may experience: Reduced nutrient absorption, limiting resources for tissue repair Increased systemic inflammation, slowing recovery Immune disruption, affecting overall healing This is why some physicians consider gut support as a complement to musculoskeletal recovery, especially after surgery or during inflammation-driven conditions

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Numerous peptides have found applications in treating orthopedic disorders, 12 with some already being used in clinical trials and preclinical studies (Table 1)

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