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12, 16, 18 A high degree of synergistic enhancement of L-PAM cytotoxicity in the presence of BSO was observed in multidrug-resistant neuroblastoma cell lines, including those that were established at relapse after myeloablative therapy with L-PAM and lines highly resistant to L-PAM due to loss of p53 function, especially at concentrations of L-PAM that were myeloablative

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Carrasco Lopez J

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The GSH administration lowered ROS production and lipid peroxidation, indicating reduced oxidative stress

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Given that these concepts may be unfamiliar to Western audiences, we provide a brief explanation to facilitate understanding of the relevant results

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