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They have been in the market since the 1940s and, by 2017, their global market was valued at more than USD 130 billion [79]

Classical and alternative pathways of the reninangiotensinaldosterone system in regulating blood pressure in hypertension and obese adolescents

Clin Cancer Res 2002;8:2985-91

One of the widely used, systemic agents is glutathione, a thiol compound and one of the regulators of melanogenic pathway in the human system

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