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Sanger sequencing has since confirmed that rare variants in these genes are implicated in the susceptibility to TS in both a European and Canadian cohort (Alexander et al., 2016)
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Epalrestat is a potent ARI-induced chemosensitivity to doxorubicin and sorafenib through inhibition of AKR1B1 and/or AKR1B10 and blockade of the EMT [145]
Studies have explored its impact on a wide range of health areas, especially related to respiratory, liver, and immune health
doi: 10.1155/2020/9494528
