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There's so many newer gene therapies and mRNA and siRNA

In other words, Cbl deficiency neurological symptoms can manifest as myelopathy, axonopathy, neuropathy, vision impairment, and paresthesia [79, 81]

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Common side effects may include mild scalp irritation like redness, itching or dryness, particularly with topical applications

It did not automatically add it to the approved list
