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Golgi stress response reprograms cysteine metabolism to confer Cytoprotection in Huntington's disease

Increased Cell Adhesion to Extracellular Matrix (ECM) Extracellular matrix is a non-cellular highly dynamic essential support structure within tissues (Ramteke et al., 2015)

Expression of the Human Isoform of Glutamate Dehydrogenase, hGDH2, Augments TCA Cycle Capacity and Oxidative Metabolism of Glutamate During Glucose Deprivation in Astrocytes. Glia 65: 474488

and a linker segment called L1

This protective effect goes beyond memory, supporting brain functions like language, problem-solving, and emotional regulation