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Chronically high levels can cause fat accumulationespecially around the waistand weak bones and muscles

Personalized gut mucosal colonization resistance to empiric probiotics is associated with unique host and microbiome features

While this review emphasizes BAs, other gut microbiota-derived metabolites (e.g., inosine, short-chain fatty acids) also regulate CD8 + T cells through distinct pathways (63, 65, 66)

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