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(2015) stated that the Hg in swordfish is absorbed more efficiently in rats when it is co-ingested with green tea extract

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Gaps in safety assessment encompass limited long-term data in vulnerable populations, an incomplete understanding of horizontal gene transfer related to antimicrobial resistance, and uncertainty regarding the systemic impact of prolonged microbiome modulation, particularly with next-generation strains lacking a long history of safe use (142)

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This reduces the synthesis of types I and III procollagen, thereby damaging the formation of new collagen while also degrading it