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When peroxynitrite accumulates, it oxidizes BH4, converting it into BH2

The gasotransmitter hydrogen sulfide induces nrf2-target genes by inactivating the keap1 ubiquitin ligase substrate adaptor through formation of a disulfide bond between cys-226 and cys-613

We found that concentrations of AS higher than 0.2 mM result in the highest HNO-specific oxidation state, peaking at modification of ~6% of total protein (Fig

Black Box Warning: HEPATITIS Severe & sometimes fatal hepatitis has been associated with isoniazid therapy

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