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Acknowledgements This work was supported by the Zhejiang Provincial Natural and Science Foundation of China under Grant (LD22H310004), Zhejiang Provincial Natural and Science Foundation (LQN25C070001), Zhejiang Sci-Tech University Research Start-up Fund (24042191-Y)

This study demonstrated that metabolomics analysis before drug exposure could shed light on the degree of drug-induced hepatotoxicity, a common side effect of acetaminophen [86]

By modulating cytokines and inflammatory markers, these peptides support systemic inflammation control and reduce gut inflammation that can interfere with recovery

The frequency and risk factor of SCD were distinct in PD with and without MCI, which suggested that SCD in early PD with different cognitive status appears to have different pathogenicity (Pan et al., 2021)