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A 3D spheroid model of primary human hepatocytes revealed that Wnt/catenin signaling induces major hepatocyte proliferation by suppressing the p53PAI1 signaling axis

However, we have identified the trace aminergic system, which functions at the level of both the brain and gut (albeit at different levels of abundance), as potential target for modulation in the context of ASD

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Zhao HM, Xu R, Huang XY, Cheng SM, Huang MF, Yue HY, et al

Despite this physical separation, gut microbiota can deeply modulate epithelial cells and the immune system ( de novo synthesized metabolites such as short-chain fatty acids (SCFAs)