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The food matrix itself, composed of fibers, proteins, and complex cell wall structures, can entrap polyphenols and hinder their release during digestion, though cooking and processing often disrupt these barriers, enhancing bioaccessibility through increased solubility and matrix breakdown (Shahidi & Pan, 2022)

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Lee NC, Tang NL, Chien YH, Chen CA, Lin SJ, Chiu PC, et al

Reduced plasma ascorbic acid concentrations in nonsmokers regularly exposed to environmental tobacco smoke