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Nese Atabey, Dokuz Eylul University, Turkey Updates Copyright 2020 Wang, Rao, Lou, Li, Liu, Li, Cui, Ren and Yu

[25] [26] Based on its overexpression in a majority of human tumor cell lines and prevalence in chemotherapeutic-resistant tumors, GSTP1-1 is thought to play a role in the development of cancer and its potential resistance to drug treatment

The mechanism involves the dependence of key family members of AP-1 and NFB on Nrf1 and Nrf2 for their expression (Yang et al., 2005a)
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H., Lee, J
