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Each cycle builds on the tissue changes from the previous one, and patients who maintain protocol adherence over 6 to 12 months of treatment typically report the most meaningful transformation in how their body responds to training

doi: 10.1590/S1807-59322011000800025 124 GustafsenCOlsenDVilstrupJLundSReinhardtAWellnerNet al

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G6PD mutation is more severe, and even the very young RBCs are depleted of the G6PD enzyme