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Finally, the safety and feasibility of combining poly(I:C) with RT for treating advanced HCC patients were further verified in a prospective clinical trial

Several of these metabolites have already been explored as candidate biomarkers and therapeutic targets in preclinical studies [165]

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Published research has shown that pre-treatment for 72 hours of human promyelocytic leukemia (HL-60)cells with calcitriol or its new analogues significantly potentiated their sensitivity to the antiproliferative effect in vitro of cisplatin, doxorubicin or genistein