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They are typically caused by an allergic reaction, physical triggers, or underlying conditions

TD-1473 is an oral pan-JAK inhibitor designed to inhibit the JAK family of enzymes locally in the GI mucosa while minimizing systemic exposure through limited oral absorption and rapid systemic clearance

Soher B, Semanchuk P, Todd D, Steinberg J, Young K

Deficiencies in vitamin B12 can lead to symptoms like headaches, fatigue, irritability, depression, anxiety, numbness and tingling in extremities, digestive problems and even nerve damage and cognitive issues

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