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In addition, NRF2 is capable of increasing the expression of many autophagy-related genes that present a common ARE sequence in their promoters, including Sequestosome-1 ( SQSTM1 ) gene (encoding protein 62) [164], and of attenuating inflammation by blocking pro-inflammatory cytokine (IL-6 and IL-1) transcription [132], thus highlighting its crucial contribution to different cellular pathways

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For example, the antimicrobial peptide CATH-2 has been reported to modulate the inflammatory response by regulating the secretion of inflammatory cytokines and activation of the NLRP3 inflammasome, resulting in protection against IAV infection (Coorens et al., Today, multiple treatments and drugs have no significant effect on Bell's palsy, the most common form of peripheral facial palsy (Gronseth and Paduga, 2014

I was surprised by the number of steps included and how involved it ended up being

The fundamental processes underlying control of the cellular redox environment will now be discussed