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demonstrated that the co-administration of Diane-35 and metformin resulted in decreased androgen receptor expression, increased GLUT4 expression, and modulation of cellular autophagy initiation by inhibiting IGF-1, ultimately leading to the suppression of EC development mediated by the mTORC pathway (Liu Y

Semen analysis focused on sperm concentration, progressive sperm motility, and normal sperm morphology

These effects are exacerbated by low folate intake

Le Trong I, Stenkamp RE, Ibarra C, Atkins WM, Adman ET

Administration of cyclophosphamide to rats induces pica and potentiates 5-hydroxytryptamine synthesis in the intestine without causing severe intestinal injury