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Dysregulation of ketone metabolism contributes to the pathologies of some cardiometabolic diseases and can lead to insulin resistance

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The lipid solution was prepared by dissolving lipids in 90% EtOH at a total concentration of 1.5 mg/mL consisting of 35 mol% complexing lipid (C12-200, DDA, or DOTAP), 49 mol% cholesterol (Sigma), and 16 mol% 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (Avanti Polar Lipids)

Therefore, while the model possesses strong learning ability on the training set, the models capacity to generalize to novel data is compromised beyond epoch 16