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512 Cancer immunotherapy has emerged a promising method for treating cancer patients, and there exists significant differences in the microbial diversity and composition of fecal samples between immunotherapy responders and non-responders, indicating that changes in clinical response may be related to the gut microbiome

Here, we report our discovery that masked nitrile-oxide electrophiles, which have not been explored previously as covalent cellular probes, undergo remarkable chemical transformations in cells and provide an effective strategy for selective targeting of GPX4

Antioxidant levels in the body do not change overnight

FoxO1 as a tissue-specific therapeutic target for type 2 diabetes

One significant underlying mechanism is arterial stiffness, with resulting structural and functional vascular alterations