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glutathione pyridyl disulfide Glutathione: a very efficient antioxidant. Abbreviation: GSSG, where one binds to reduced nicotinamide adenine dinucleotide phosphate (NADPH) and flavin adenine dinucleotide (FAD) the second one is an interface dimerization domain Glutathione-triggered biodegradable poly(disulfide)s: ring-opening copolymerization

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10.1016/j.redox.2021.102122 179 RuiuR.RolihV.BolliE.BarutelloG.RiccardoF.QuaglinoE.et al (2019)

glutathione pyridyl disulfide Glutathione: a very efficient antioxidant. Abbreviation: GSSG, where one binds to reduced nicotinamide adenine dinucleotide phosphate (NADPH) and flavin adenine dinucleotide (FAD) the second one is an interface dimerization domain Glutathione-triggered biodegradable poly(disulfide)s: ring-opening copolymerization

The increased levels of glutamine could be to deal with the excitotoxicity effects of the pesticide

glutathione pyridyl disulfide Glutathione: a very efficient antioxidant. Abbreviation: GSSG, where one binds to reduced nicotinamide adenine dinucleotide phosphate (NADPH) and flavin adenine dinucleotide (FAD) the second one is an interface dimerization domain Glutathione-triggered biodegradable poly(disulfide)s: ring-opening copolymerization

Antioxidants as Pro-oxidants Chapter 1 described a clinical trial that found that high-dose beta-carotene supplementation increased lung cancer risk in smokers

glutathione pyridyl disulfide Glutathione: a very efficient antioxidant. Abbreviation: GSSG, where one binds to reduced nicotinamide adenine dinucleotide phosphate (NADPH) and flavin adenine dinucleotide (FAD) the second one is an interface dimerization domain Glutathione-triggered biodegradable poly(disulfide)s: ring-opening copolymerization

In addition, it was proven that inducible knockout of GPX4 could make acute kidney failure through the ferroptotic pathway [33]

glutathione pyridyl disulfide Glutathione: a very efficient antioxidant. Abbreviation: GSSG, where one binds to reduced nicotinamide adenine dinucleotide phosphate (NADPH) and flavin adenine dinucleotide (FAD) the second one is an interface dimerization domain Glutathione-triggered biodegradable poly(disulfide)s: ring-opening copolymerization

10.3892/mmr.2017.6377 6

glutathione pyridyl disulfide Glutathione: a very efficient antioxidant. Abbreviation: GSSG, where one binds to reduced nicotinamide adenine dinucleotide phosphate (NADPH) and flavin adenine dinucleotide (FAD) the second one is an interface dimerization domain Glutathione-triggered biodegradable poly(disulfide)s: ring-opening copolymerization

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