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Regional distribution of manganese, iron, copper, and zinc in the rat brain during development

[PubMed] [Google Scholar] 105.PCO-02Safety and Pharmacokinetics Trial NCT02637284

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PIMT methylates the -carboxyl group of isoAsp and facilitates the formation of succinimide, which can react with a nucleophile, such as H 2 18 O, to generate labeled isoAsp residues
The extracellular region of RAGE comprises a variable (V) immunoglobulin (Ig) domain followed by two constant Ig domains (C1 and C2), which are connected by a flexible linker [222]