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acknowledges support from the National Institutes of Health (NIH) (P50CA272218) and the Melanoma Research Foundation

[sources 14] Animal models of neurotoxicity from high-dose amphetamine exposure indicate that the occurrence of hyperpyrexia (i.e., core body temperature 40 C) is necessary for the development of amphetamine-induced neurotoxicity

Xu H, Wang J, Liang Y, Fu Y, Li S, Huang J, et al

Second, the niosomal bilayer structure enables controlled and sustained drug release, as the vesicles gradually release their cargo over an extended period rather than releasing it all at once [122,124]