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We recommend applying twice a day - first thing in the morning and then again before bed

"Principles of long-term dynamics of dendritic spines." J Neurosci 28: 13592-608

10.1046/j.1471-4159.1994.63051987.x J

Likewise, alteration in glucose and lipid metabolisms were reported to contribute to neuronal vulnerability in diseased motor neurons 50
