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doi: 10.1155/2018/7918714 31 SrinivasPRWagnerASReddyLVDeutschDDLeonMAGoustinASet al

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Boveris A, Chance B (1973) The mitochondrial generation of hydrogen peroxide
Androgen/AR complex binding to antioxidative response elements (AREs) containing promoters of target genes disrupts Wnt agonist/antagonist balance involved in DPC-inductive ability, such as dickkopf-1 (DKK1), which is a specific inhibitor of Wnt coreceptors of the LRP family 29

26 This may be due in part to age-related changes in cochlear structures and nerve function and connectivity
