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In this context, cocaine, diamorphine (heroin), methylenedioxymethamphetamine (MDMA/ecstasy) and tetrahydrocannabinol (THC) are designated as Substances of Abuse

MITF activation drives the expression of melanogenic enzymes including tyrosinase, TRP-1, and TRP-2, which are essential for eumelanin synthesis (Barnetson et al., 2006)

Zodasiran, a siRNA inhibiting ANGPTL3 mRNA, has not yet received the EMA and FDA approval (phase 3 randomized controlled trial ongoing)

Diseases, such as cardiovascular disorders, are associated with inadequate concentrations of l-ascorbic acid, tocopherol, and -carotene [810] in epidemiological studies

Additional reporting by Colette Howe and Jessica Ure