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These leukocytes are the phagocytic cells of the immune system and they utilize NADPH to generate superoxide radicals from molecular oxygen in a reaction catalyzed by one of the NADPH oxidase complexes

This increased stability keeps the glutathione molecule intact as it is absorbed and used by the body

When GPX is disabled due to a defect in glutathione recycling, the redox state of red blood cells shifts toward an oxidative stage, which impairs deformability

doi: 10.1249/01.MSS.0000069553.47739.36

Many previous studies recruited children with ASD from ages 218, which may have resulted in non-significant findings