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10.1007/s00109-015-1310-2 115 RobertiA.FernndezA

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248.Ravussin E, Smith SR, Mitchell JA, et al

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Simultaneously, higher S-adenosylmethionine (SAM) availability supports key methylation-dependent pathways, which are crucial for epigenetic regulation and gene expression related to energy metabolism

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NHS loading is 1mg hydroxocobalamin every two days for two weeks, then maintenance every two to three months for life when the cause is non-dietary

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