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Description
Metabolic changes at the micro level (cellular functions, membranes, mitochondria) lead to macro alterations that impact the body as a whole and eventually manifest as age-related chronic and degenerative diseases

PEA is the most widely studied compound for modulating mast cell activation and restoring hyperactive glial cells to their physiological function, says Coluzzi

Additional information Competing interests The author(s) declare that they have no competing interests

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In contrast, in our rat model of pressure overload, we also observed improved functional outcome and preserved cardiac glucose oxidation without changes in insulin levels, 143 which suggest insulin-independent effects of GLP-1
