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Clinical Chemistry 50 (1): 332
A third category targets fat cells directly rather than working through appetite or growth-hormone pathways

Clinical trials show 15-22% weight loss with semaglutide and up to 24% with tirzepatide over 68 weeks
Convenient and Efficient: Direct delivery allows for better absorption compared to oral supplements

Within this group of 39 individuals, 9 had been randomised to placebo, 17 to Vitamin-B6 and 13 to Vitamin-B12